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Title:Computer Applications in Pharmaceutical Research and Development
Format Type:Ebook
Author:
Publisher:Wiley-Interscience
ISBN:0471737798
ISBN 13:
Number of Pages:805
Category:Manga

Computer Applications in Pharmaceutical Research and Development by Sean Ekins

PDF, EPUB, MOBI, TXT, DOC Computer Applications in Pharmaceutical Research and Development A unique holistic approach covering all functions and phases of pharmaceutical research and development .

While there are a number of texts dedicated to individual aspects of pharmaceutical research and development this unique contributed work takes a holistic and integrative approach to the use of computers in all phases of drug discovery development and marketing It explains how applications are used at various stages including bioinformatics data mining predicting human response to drugs and high throughput screening By providing a comprehensive view the book offers readers a unique framework and systems perspective from which they can devise strategies to thoroughly exploit the use of computers in their organizations during all phases of the discovery and development process .

Chapters are organized into the following sections Computers in pharmaceutical research and development a general overview Understanding diseases mining complex systems for knowledge Scientific information handling and enhancing productivity Computers in drug discovery Computers in preclinical development Computers in development decision making economics and market analysis Computers in clinical development Future applications and future development .

Each chapter is written by one or more leading experts in the field and carefully edited to ensure a consistent structure and approach throughout the book Figures are used extensively to illustrate complex concepts and multifaceted processes References are provided in each chapter to enable readers to continue investigating a particular topic in depth Finally tables of software resources are provided in many of the chapters .

This is essential reading for IT professionals and scientists in the pharmaceutical industry as well as researchers involved in informatics and ADMET drug discovery and technology development The book s cross functional all phases approach provides a unique opportunity for a holistic analysis and assessment of computer applications in pharmaceutics

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Computational Toxicology: Risk Assessment for Chemicals, The Engines of Hippocrates: From the Dawn of Medicine to Medical and Pharmaceutical Informatics, Collaborative Computational Technologies for Biomedical Research, Computational Toxicology: Risk Assessment for Chemicals, Computational Toxicology: Risk Assessment for Chemicals, Drug Efficacy, Safety, and Biologics Discovery: Emerging Technologies and Tools (Wiley Series on Technologies for the Pharmaceutical Industry #4), Computational Toxicology: Risk Assessment for Pharmaceutical and Environmental Chemicals, Computer Applications in Pharmaceutical Research and Development, Pharmaceutical and Biomedical Project Management in a Changing Global Environment, The Future of the Pharmaceutical Industry
The Future of the Pharmaceutical Industry presents the main problems and challenges facing the industry today through a series of candid and thought provoking interviews with managers business leaders and scientists in pharma biotech and academia in the US and abroad Key topics include the economics of blockbusters emerging generics regulatory restrictions encouraging collaboration incremental and disruptive innovation empowering co creation and much more This timely and insightful book is presented as an active debate to show different perspectives experiences and insights and provide readers with a discussion of solutions and strategies to address these problems br Provides a greater understanding of the history and driving factors behind the challenges currently facing the pharmaceutical industry through interviews with executives business leaders and key researchers in pharma biotech and academia br br Presented in an active debate format to portray differing opinions on the future of the pharmaceutical industry br br Illustrates how the pieces fit together through candid discussions and offers solutions and strategies to adapt to a changing landscape br br Focuses on collaboration experiences and innovation to allow the reader to formulate their own vision of the future, i Pharmaceutical and Biomedical Portfolio Management in a Changing Global Environment i explores some of the critical forces at work today in the complex endeavour of pharmaceutical and medical product development Written by experienced professionals and including real world approaches and best practice examples this new title addresses three key areas small molecules large molecules and medical devices and provides hard to find consolidated information relevant to and needed by pharmaceutical biotech and medical device company managers, A unique integrative look at information based medicine The convergence of medical science biology pharmacology biomedical engineering healthcare and information technology is revolutionizing medical and scientific practice and has broader social implications still being understood i The Engines of Hippocrates i provides a unique integrative and holistic look at the new paradigm of information based medicine covering a broad range of topics for a wide readership br br The authors take a comprehensive approach examining the prehistory history and future of medicine and medical technology and its relation to information how history led to such present day discoveries as the structure of DNA the human genome and the discipline of bioinformatics and what the future results of these discoveries may hold Their far ranging views are their own and not necessarily those of the IBM Corporation or other employers br br i The Engines of Hippocrates i helps readers understand br br br Forces shaping the pharmaceutical and biomedical industries today including personalized medicine genomics data mining and bionanotechnology The relationship between pharmaceutical science today and other disciplines such as philosophy of health history economics mathematics and computer science br br The integrated role alternative and non Western medicines could play in a new information based medicine br br Practical ethical organizational technological and social problems of information based medicine along with a novel data centric computing model and a self adaptive software engineering model and corresponding information technology architectures including perspectives on sharing remote data efficiently and securely for the common good br br An unmatched cross disciplinary perspective on the big picture of today and tomorrow s medicine i The Engines of Hippocrates i provides a reference to interested readers both inside and outside the pharmaceutical and medical communities as well as a peerless classroom supplement to students in a wide variety of disciplines, br A key resource for toxicologists across a broad spectrum of fields this book offers a comprehensive analysis of molecular modelling approaches and strategies applied to risk assessment for pharmaceutical and environmental chemicals br br Provides a perspective of what is currently achievable with computational toxicology and a view to future developments br Helps readers overcome questions of data sources curation treatment and how to model interpret critical endpoints that support st century hazard assessment br Assembles cutting edge concepts and leading authors into a unique and powerful single source reference br Includes in depth looks at QSAR models physicochemical drug properties structure based drug targeting chemical mixture assessments and environmental modeling br Adds coverage about consumer product safety assessment and chemical defense along with chapters on open source toxicology and big data